Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340946 | 0.90 | HTR4 (0.47) | KMT2AMEN1HTR4AGTR1 | |
| SCHEMBL9704184 | 0.85 | HTR4 (0.44) | HTR4AGTR1 | |
| SCHEMBL7323669 | 0.83 | HTR4 (0.39) | HTR4AGTR1 | |
| SCHEMBL7302809 | 0.77 | HTR4 (0.48) | KMT2AMEN1ALDH1A1CCR3HTR4 | |
| SCHEMBL7322685 | 0.71 | CYP2C9 (0.51) | KMT2AMEN1HTR4AGTR1 | |
| SCHEMBL7304670 | 0.69 | KDM1A (0.46) | OPRM1KDM4EMAPTHTR7ALDH1A1 | |
| SCHEMBL7301885 | 0.65 | HTR4 (0.67) | KMT2AMEN1ALDH1A1HTR4AGTR1 | |
| Hydrochloric Acid SCHEMBL9540264 | 0.65 | KCNH2 (0.43) | KDM4EHTR7ALDH1A1HTR4 | |
| SCHEMBL7302843 | 0.64 | KDM4E (0.44) | KMT2AKDM4EMEN1MAPTHTR7 | |
| SCHEMBL7300816 | 0.64 | HTR4 (0.54) | KMT2AMEN1ALDH1A1HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0501322-A1 | 3-Piperidinylmethylcarboxylate substituted indoles | GLAXO GROUP LIMITED (GB) | 1992-09-02 | — | — | EP | disclosed |