Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7300755 | 0.88 | KDM4E (0.46) | KDM4EMAPTHTR7HTR4EGFR | |
| SCHEMBL9341470 | 0.86 | HTR4 (0.50) | KDM4EHTR7NPSR1HTR4ALDH1A1 | |
| SCHEMBL7301395 | 0.85 | HTR7 (0.46) | KDM4EMAPTHTR7HTR4EGFR | |
| SCHEMBL7304868 | 0.84 | SLC6A2 (0.47) | KDM4EMAPTHTR7 | |
| SCHEMBL7303046 | 0.84 | ALDH1A1 (0.46) | KDM4EMAPTHTR7NPSR1MEN1 | |
| SCHEMBL9344433 | 0.83 | CCR1 (0.46) | KDM4EMAPTHTR7EGFRNPY1R | |
| SCHEMBL4294891 | 0.81 | HTR4 (0.55) | KDM4EMAPTHTR7NPSR1HTR4 | |
| SCHEMBL7309279 | 0.81 | KDM1A (0.45) | KDM4EMAPTHTR7HTR4EGFR | |
| SCHEMBL7304670 | 0.81 | KDM1A (0.46) | KDM4EMAPTHTR7EGFRALDH1A1 | |
| SCHEMBL7307824 | 0.80 | HTR4 (0.49) | MAPTHTR7NPSR1HTR4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0501322-B1 | 3-Piperidinylmethylcarboxylate substituted indoles | GLAXO GROUP LTD (GB) | 1996-09-04 | — | — | EP | claimed |