Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 6/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325668 | 0.90 | OPRM1 (0.37) | HTR4KMT2AMEN1AGTR1 | |
| SCHEMBL9704184 | 0.87 | HTR4 (0.44) | HTR4CYP2C9PMP22NPSR1CYP1A2 | |
| SCHEMBL7323669 | 0.83 | HTR4 (0.39) | HTR4CYP2C9PMP22NPSR1CYP1A2 | |
| SCHEMBL7302809 | 0.82 | HTR4 (0.48) | HTR4CYP2C9PMP22NPSR1CYP1A2 | |
| SCHEMBL7301885 | 0.81 | HTR4 (0.67) | HTR4CYP2C9PMP22NPSR1CYP1A2 | |
| SCHEMBL7322685 | 0.80 | CYP2C9 (0.51) | HTR4CYP2C9PMP22NPSR1CYP1A2 | |
| SCHEMBL16504002 | 0.73 | CYP2C9 (0.66) | HTR4CYP2C9PMP22NPSR1CYP1A2 | |
| SCHEMBL7324773 | 0.71 | HTR4 (0.69) | HTR4CYP2C9PMP22NPSR1CYP1A2 | |
| SCHEMBL4294891 | 0.70 | HTR4 (0.55) | HTR4CYP2C9PMP22NPSR1CYP1A2 | |
| SCHEMBL7300816 | 0.69 | HTR4 (0.54) | HTR4CYP2C9PMP22NPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0501322-B1 | 3-Piperidinylmethylcarboxylate substituted indoles | GLAXO GROUP LTD (GB) | 1996-09-04 | — | — | EP | disclosed |