Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7336032 | 0.76 | OPRD1 (0.31) | OPRD1 | |
| SCHEMBL9280928 | 0.67 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL7333320 | 0.66 | SLC6A4 (0.34) | OPRD1ALDH1A1KDM4EMEN1RECQL | |
| Hydrochloric Acid SCHEMBL9198794 | 0.64 | SLC6A4 (0.36) | OPRD1ALDH1A1KDM4EMEN1RECQL | |
| SCHEMBL7326487 | 0.63 | HTR1A (0.36) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7324373 | 0.62 | HTR1A (0.36) | ALDH1A1 | |
| SCHEMBL9196790 | 0.61 | CNR2 (0.42) | OPRD1KDM4E | |
| Hydrochloric Acid SCHEMBL28034689 | 0.59 | CPN1 (0.57) | OPRD1 | |
| SCHEMBL15058450 | 0.58 | SLC6A2 (0.44) | OPRD1ALDH1A1KMT2A | |
| SCHEMBL27838149 | 0.58 | KDM4E (0.47) | ALDH1A1KDM4EMEN1RECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994008994-A1 | HETEROCYCLIC -ESTERS OR -AMIDES USED AS 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-04-28 | — | — | WO | claimed |
| US-5708174-A | Heterocyclic-esters or -amides used as 5-HT4 receptor antagonists | SMITHKLINE BEECHAM P.L.C. (GB) | 1998-01-13 | — | — | US | disclosed |
| EP-0664805-A1 | HETEROCYCLIC -ESTERS OR -AMIDES USED AS 5-HT 4? RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-08-02 | — | — | EP | disclosed |
| WO-1994008994-A1 | HETEROCYCLIC -ESTERS OR -AMIDES USED AS 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-04-28 | — | — | WO | disclosed |