Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GLS | O94925 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9198794 | 0.76 | SLC6A4 (0.36) | SLC6A4SLC6A2SLC6A3OPRD1KCNH2 | |
| SCHEMBL9196790 | 0.74 | CNR2 (0.42) | SLC6A4SLC6A2SLC6A3OPRD1CNR1 | |
| SCHEMBL7346880 | 0.68 | OXER1 (0.36) | SLC6A4SLC6A2SLC6A3OPRD1KCNH2 | |
| SCHEMBL7328048 | 0.67 | PTGER1 (0.39) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL7325733 | 0.66 | OPRD1 (0.32) | OPRD1ALDH1A1KDM4EMEN1RECQL | |
| SCHEMBL7336032 | 0.65 | OPRD1 (0.31) | SLC6A4SLC6A2SLC6A3OPRD1 | |
| SCHEMBL25119667 | 0.64 | CA2 (0.37) | CNR1CNR2KDM4EMEN1RECQL | |
| SCHEMBL7326487 | 0.64 | HTR1A (0.36) | ALDH1A1SMYD3 | |
| SCHEMBL7348377 | 0.64 | GAA (0.37) | SLC6A4SLC6A2SLC6A3OPRD1SMYD3 | |
| SCHEMBL7333317 | 0.64 | HTR4 (0.45) | SLC6A4SLC6A2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664806-A1 | HETEROCYCLIC CONDENSED BENZOIC ACID DERIVATIVES AS 5-HT 4? RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-08-02 | — | — | EP | claimed |
| WO-1994008995-A1 | HETEROCYCLIC CONDENSED BENZOIC ACID DERIVATIVES AS 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-04-28 | — | — | WO | claimed |