Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9344979 | 0.85 | HTR4 (0.55) | HTR4 | |
| SCHEMBL8508371 | 0.84 | HTR4 (0.52) | HTR4NR4A2 | |
| SCHEMBL7421473 | 0.83 | HTR4 (0.53) | HTR4 | |
| SCHEMBL7429744 | 0.80 | HTR4 (0.80) | HTR4NR4A2 | |
| SCHEMBL6952214 | 0.79 | GSK3B (0.62) | — | |
| SCHEMBL9341292 | 0.75 | KDM4E (0.49) | — | |
| SCHEMBL9345077 | 0.74 | KDM4E (0.46) | HTR4 | |
| Piboserod SCHEMBL467339 | 0.73 | HTR4 (1.00) | HTR4 | |
| Piboserod SCHEMBL30234609 | 0.73 | HTR4 (1.00) | HTR4 | |
| SCHEMBL9340440 | 0.73 | ALOX15 (0.53) | HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998409-A | GASTROINTESTINAL DISORDERS; CARDIOVASCULAR DISORDERS; NERVOUS SYSTEM DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 1999-12-07 | — | — | US | disclosed |
| EP-0630376-B1 | CONDENSED INDOLE DERIVATIVES AS 5-HT4-RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1999-06-02 | — | — | EP | disclosed |
| US-5852014-A | Condensed indole derivatives as 5HT4 -receptor antagonists | SMITHKLINE BEECHAM P.L.C. (GB) | 1998-12-22 | — | — | US | disclosed |
| EP-0630376-A1 | CONDENSED INDOLE DERIVATIVES AS 5HT 4?-RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-12-28 | — | — | EP | disclosed |
| WO-1993018036-A1 | CONDENSED INDOLE DERIVATIVES AS 5HT4-RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-09-16 | — | — | WO | disclosed |