Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 12/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4671256 | 1.00 | MGLL (0.46) | MGLLMEN1KMT2ALMNATP53 | |
| SCHEMBL8149178 | 0.90 | MGLL (0.48) | MGLLMEN1KMT2ALMNATP53 | |
| SCHEMBL8140788 | 0.84 | ALDH1A1 (0.48) | MGLLMEN1KMT2ALMNATP53 | |
| SCHEMBL8105525 | 0.84 | MGLL (0.43) | MGLLMEN1KMT2ALMNATP53 | |
| SCHEMBL8147774 | 0.82 | KDM2B (0.55) | MGLLLMNATP53MAPTL3MBTL1 | |
| SCHEMBL8154882 | 0.82 | MGLL (0.43) | MGLLMEN1KMT2ALMNATP53 | |
| SCHEMBL8111407 | 0.82 | LMNA (0.46) | MGLLMEN1KMT2ALMNATP53 | |
| SCHEMBL8150423 | 0.82 | LMNA (0.45) | MGLLMEN1KMT2ALMNATP53 | |
| SCHEMBL8109739 | 0.82 | MGLL (0.45) | MGLLMEN1KMT2ALMNATP53 | |
| SCHEMBL4671309 | 0.82 | MGLL (0.43) | MGLLMEN1KMT2ALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376506-B1 | REACTING SULFAMOYL OXAZOLIDONE WITH (1,2,3,4)-TETRAHYDRO-BETA-CARBOLINE TO FORM INHIBITOR; USED TO TREAT ARTHRITIS, OSTEOPOROSIS, PERIODONTAL DISEASE, CARDIOVASCULAR DISEASES, MULTIPLE SCLEROSIS, AND TUMORS | SYNTEX (U.S.A.) LLC | 2002-04-23 | — | — | US | disclosed |