Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 10/20 | 0.48 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325935 | 0.90 | MGLL (0.46) | MGLLKDM2BLMNAMEN1KMT2A | |
| SCHEMBL4671256 | 0.90 | MGLL (0.46) | MGLLKDM2BLMNAMEN1KMT2A | |
| SCHEMBL8140788 | 0.87 | ALDH1A1 (0.48) | MGLLLMNAMEN1KMT2ATP53 | |
| SCHEMBL8105525 | 0.87 | MGLL (0.43) | MGLLLMNAMEN1KMT2ATP53 | |
| SCHEMBL8105681 | 0.86 | L3MBTL3 (0.45) | MGLLLMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL8147774 | 0.85 | KDM2B (0.55) | MGLLKDM2BLMNATP53MAPT | |
| SCHEMBL8103919 | 0.84 | KDM2B (0.47) | MGLLKDM2BLMNAMEN1KMT2A | |
| SCHEMBL8109739 | 0.84 | MGLL (0.45) | MGLLLMNAMEN1KMT2ATP53 | |
| SCHEMBL8154882 | 0.84 | MGLL (0.43) | MGLLLMNAMEN1KMT2ATP53 | |
| SCHEMBL8111407 | 0.84 | LMNA (0.46) | MGLLKDM2BLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130220-A | ENZYME INHIBITORS | SYNTEX (USA) INC. (US) | 2000-10-10 | — | — | US | disclosed |