Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 5/20 | 0.44 |
| ▸ | CTSD | P07339 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 7/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7331769 | 0.84 | BACE1 (0.48) | BACE1CTSDTSHRPSMB5METAP2 | |
| SCHEMBL7323598 | 0.84 | BACE1 (0.48) | BACE1CTSDTSHRPSMB5METAP2 | |
| SCHEMBL7326963 | 0.82 | CTSS (0.40) | BACE1CTSDTSHRPSMB5REN | |
| SCHEMBL10378722 | 0.81 | BACE1 (0.50) | BACE1CTSDMEN1KMT2A | |
| SCHEMBL10378648 | 0.81 | BACE1 (0.50) | BACE1CTSDMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7321431 | 0.80 | BACE1 (0.49) | BACE1CTSDMEN1KMT2A | |
| SCHEMBL7330273 | 0.78 | REN (0.36) | BACE1CTSDMETAP2RENMETAP1 | |
| SCHEMBL7324941 | 0.76 | BACE1 (0.39) | BACE1CTSDTSHRPSMB5REN | |
| SCHEMBL7359787 | 0.73 | REN (0.42) | BACE1CTSDMETAP2RENMETAP1 | |
| SCHEMBL25582716 | 0.72 | TSHR (0.58) | TSHRHPGDALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | claimed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | claimed |
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |