Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 5/20 | 0.36 |
| ▸ | CTSD | P07339 | 4/20 | 0.36 |
| ▸ | METAP2 | P50579 | 7/20 | 0.36 |
| ▸ | METAP1 | P53582 | 3/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324457 | 0.82 | BACE1 (0.41) | RENBACE1CTSDMETAP2 | |
| SCHEMBL7325941 | 0.78 | BACE1 (0.44) | RENBACE1CTSDMETAP2METAP1 | |
| SCHEMBL7359787 | 0.77 | REN (0.42) | RENBACE1CTSDMETAP2METAP1 | |
| SCHEMBL7369089 | 0.67 | REN (0.50) | RENMETAP2METAP1CTSK | |
| SCHEMBL7368676 | 0.67 | REN (0.50) | RENMETAP2METAP1CTSK | |
| SCHEMBL27280087 | 0.66 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL10589195 | 0.66 | REN (0.43) | RENMETAP2METAP1CTSK | |
| SCHEMBL7368293 | 0.65 | REN (0.42) | RENMETAP2METAP1CTSK | |
| SCHEMBL7362228 | 0.65 | REN (0.42) | RENMETAP2METAP1CTSK | |
| SCHEMBL17958890 | 0.65 | CTSC (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |