Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | CPB1 | P15086 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10594095 | 0.81 | SLC6A4 (0.43) | SLC6A4SLC6A2CPB1CTSKFKBP1A | |
| SCHEMBL10594092 | 0.81 | SLC6A4 (0.43) | SLC6A4SLC6A2CPB1CTSKFKBP1A | |
| SCHEMBL7322950 | 0.75 | CTSK (0.50) | SLC6A4SLC6A2CTSKALDH1A1MAPT | |
| SCHEMBL7322944 | 0.75 | CTSK (0.50) | SLC6A4SLC6A2CTSKALDH1A1MAPT | |
| SCHEMBL23022877 | 0.73 | CTSK (0.47) | SLC6A4SLC6A2CPB1CTSKALDH1A1 | |
| SCHEMBL18440290 | 0.72 | SLC6A2 (0.48) | SLC6A4SLC6A2CPB1FKBP1AALDH1A1 | |
| SCHEMBL12282055 | 0.72 | CPB1 (0.57) | SLC6A4SLC6A2CPB1FKBP1AALDH1A1 | |
| SCHEMBL30763813 | 0.72 | SLC6A4 (0.45) | SLC6A4SLC6A2CPB1CTSKFKBP1A | |
| SCHEMBL354630 | 0.71 | CHRM2 (0.39) | SLC6A4SLC6A2ALDH1A1 | |
| SCHEMBL7326224 | 0.71 | GPR52 (0.41) | SLC6A4SLC6A2CPB1CTSKFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262431-A | Treating amnesia | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0275482-B1 | PROLINE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-01-20 | — | — | EP | disclosed |
| US-5112847-A | PROLINAL DERIVATIVES HAVING INHIBITORY ACTIVITY ON PROLYL ENDOPEPTIDASE | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-05-12 | — | — | US | disclosed |
| US-4983624-A | Anemia | ONO PHARMACEUTICAL CO., LTD (JP) | 1991-01-08 | — | — | US | disclosed |
| EP-0275482-A2 | Proline derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-07-27 | — | — | EP | disclosed |