Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGAV | P06756 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 3/20 | 0.48 |
| ▸ | CTSL | P07711 | 4/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 2/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323268 | 1.00 | ITGB3 (0.50) | ITGB3ITGAVTACR1CTSLCTSS | |
| SCHEMBL7330763 | 0.90 | ITGB3 (0.57) | ITGB3ITGAVTACR1CTSLCTSS | |
| SCHEMBL7330756 | 0.90 | ITGB3 (0.57) | ITGB3ITGAVTACR1CTSLCTSS | |
| SCHEMBL1824920 | 0.83 | CTSL (0.48) | ITGB3ITGAVTACR1CTSLCTSS | |
| SCHEMBL6440663 | 0.83 | CTSL (0.64) | TACR1CTSLCTSSCTSKCTSB | |
| SCHEMBL6440666 | 0.83 | CTSL (0.64) | TACR1CTSLCTSSCTSKCTSB | |
| SCHEMBL5403293 | 0.80 | GPR132 (0.56) | ITGB3ITGAV | |
| SCHEMBL27509468 | 0.80 | GPR132 (0.56) | ITGB3ITGAV | |
| SCHEMBL1826528 | 0.80 | P2RX7 (0.53) | CTSLCTSSCTSB | |
| SCHEMBL6768390 | 0.79 | ITGB3 (0.57) | ITGB3ITGAVTACR1CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658169-A1 | DIAMINO ACID DERIVATIVES AS ANTIHYPERTENSIVES | SCHERING CORPORATION (US) | 1995-06-21 | — | — | EP | disclosed |
| US-5298492-A | Inhibitors of endopeptidase and treatment of cardiovascular disorders | SCHERING CORPORATION (US) | 1994-03-29 | — | — | US | disclosed |
| WO-1994003481-A1 | DIAMINO ACID DERIVATIVES AS ANTIHYPERTENSIVES | SCHERING CORPORATION (US) | 1994-02-17 | — | — | WO | disclosed |