Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.62 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324893 | 0.93 | MTNR1A (0.65) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL7335952 | 0.88 | MTNR1A (0.60) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL7336034 | 0.85 | DRD2 (0.57) | MTNR1AMTNR1BCA1CA2ACHE | |
| Hydrochloric Acid SCHEMBL7334747 | 0.84 | DRD2 (0.56) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL7328332 | 0.83 | DRD2 (0.55) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL7328237 | 0.83 | DRD2 (0.65) | MTNR1AMTNR1BALDH1A1MEN1LMNA | |
| Hydrochloric Acid SCHEMBL7333108 | 0.82 | DRD2 (0.53) | MTNR1AMTNR1BCA1CA2ACHE | |
| Hydrochloric Acid SCHEMBL7329618 | 0.82 | DRD2 (0.64) | MTNR1AMTNR1BALDH1A1MEN1LMNA | |
| SCHEMBL7331004 | 0.81 | MTNR1A (0.60) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL7333316 | 0.81 | MTNR1A (0.67) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5196454-A | METHOD OF TREATING DISORDERS OF THE DOPAMINERGIC SYSTEMS USING 2,5-DIAMINOTETRALINES | BOEHRINGER INGELHEIM KG (DE) | 1993-03-23 | — | — | US | disclosed |
| EP-0402923-A2 | 2,5-Diaminotetralines, process for their preparation and their use as medicine | BOEHRINGER INGELHEIM KG (DE) | 1990-12-19 | — | — | EP | disclosed |