Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.42 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.42 |
| ▸ | DDAH1 | O94760 | 3/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6445484 | 0.89 | DPP7 (0.50) | DPP7SLC15A1CA1CA2SLC1A3 | |
| SCHEMBL21114423 | 0.89 | DPP7 (0.50) | DPP7SLC15A1CA1CA2SLC1A3 | |
| SCHEMBL5497695 | 0.89 | DPP7 (0.50) | DPP7SLC15A1CA1CA2SLC1A3 | |
| SCHEMBL28313344 | 0.87 | ALOX15 (0.60) | KMT2AALOX15BLMPMP22SLC1A3 | |
| SCHEMBL711607 | 0.87 | ALOX15 (0.60) | KMT2AALOX15BLMPMP22SLC1A3 | |
| SCHEMBL9522029 | 0.86 | DPP7 (0.42) | DPP7SLC15A1DDAH1NOD1CA1 | |
| SCHEMBL9665984 | 0.85 | DGKA (0.44) | KMT2AALOX15BLMPMP22CYP3A4 | |
| SCHEMBL14486146 | 0.84 | BLM (0.48) | KMT2AALOX15BLMPMP22DPP7 | |
| SCHEMBL5548781 | 0.83 | DGKA (0.47) | KMT2AALOX15BLMPMP22CYP3A4 | |
| SCHEMBL6940812 | 0.83 | DGKA (0.47) | KMT2AALOX15BLMPMP22CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815856-A2 | Retroviral protease inhibitors | MONSANTO COMPANY (US) | 1998-01-07 | — | — | EP | disclosed |
| EP-0813867-A2 | Retroviral protease inhibitors | MONSANTO COMPANY (US) | 1997-12-29 | — | — | EP | disclosed |
| EP-0813868-A2 | Retroviral protease inhibitors | MONSANTO COMPANY (US) | 1997-12-29 | — | — | EP | disclosed |
| EP-0735019-A2 | Retroviral protease inhibitors | MONSANTO COMPANY (US) | 1996-10-02 | — | — | EP | disclosed |
| EP-0731088-A2 | Retroviral protease inhibitors | MONSANTO COMPANY (US) | 1996-09-11 | — | — | EP | disclosed |
| EP-0558673-B1 | RETROVIRAL PROTEASE INHIBITORS | MONSANTO CO (US) | 1996-04-17 | — | — | EP | disclosed |
| EP-0558603-A1 | RETROVIRAL PROTEASE INHIBITORS | MONSANTO COMPANY (US) | 1993-09-08 | — | — | EP | disclosed |
| EP-0558630-A1 | RETROVIRAL PROTEASE INHIBITORS | MONSANTO COMPANY (US) | 1993-09-08 | — | — | EP | disclosed |
| EP-0558673-A1 | RETROVIRAL PROTEASE INHIBITORS. | MONSANTO CO (US) | 1993-09-08 | — | — | EP | disclosed |
| EP-0558657-A1 | RETROVIRAL PROTEASE INHIBITORS. | MONSANTO CO (US) | 1993-09-08 | — | — | EP | disclosed |
| WO-1992008700-A1 | RETROVIRAL PROTEASE INHIBITORS | MONSANTO COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |
| WO-1992008701-A1 | RETROVIRAL PROTEASE INHIBITORS | MONSANTO COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |
| WO-1992008699-A1 | RETROVIRAL PROTEASE INHIBITORS | MONSANTO COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |
| WO-1992008688-A1 | RETROVIRAL PROTEASE INHIBITORS | MONSANTO COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |