Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.42 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 5/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 3/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21114423 | 0.89 | DPP7 (0.50) | DPP7SLC15A1CA1CA2SLC1A2 | |
| SCHEMBL5497695 | 0.89 | DPP7 (0.50) | DPP7SLC15A1CA1CA2SLC1A2 | |
| SCHEMBL6445484 | 0.89 | DPP7 (0.50) | DPP7SLC15A1CA1CA2SLC1A2 | |
| SCHEMBL7326554 | 0.86 | KMT2A (0.47) | DPP7SLC15A1CA1CA2SLC1A2 | |
| SCHEMBL11061010 | 0.82 | ALOX15 (0.36) | DPP9GRIK1GRIK2 | |
| SCHEMBL995487 | 0.82 | ALOX15 (0.36) | DPP9GRIK1GRIK2 | |
| SCHEMBL27906557 | 0.82 | ALOX15 (0.36) | DPP9GRIK1GRIK2 | |
| SCHEMBL379284 | 0.82 | SLC15A1 (0.46) | DPP7SLC15A1CA1CA2SLC1A2 | |
| SCHEMBL1389422 | 0.82 | GSR (0.50) | DPP7DPP4DPP8DPP9 | |
| SCHEMBL52379 | 0.81 | DPP7 (0.51) | DPP7SLC15A1CA1CA2SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546108-A4 | PRO-DRUGS FOR CCK ANTAGONISTS | — | 1993-09-22 | — | — | EP | disclosed |
| EP-0546108-A1 | PRO-DRUGS FOR CCK ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1993-06-16 | — | — | EP | disclosed |