Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.50 |
| ▸ | CPA1 | P15085 | 3/20 | 0.48 |
| ▸ | CPB1 | P15086 | 1/20 | 0.48 |
| ▸ | CPA3 | P15088 | 1/20 | 0.48 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303707 | 1.00 | SIGMAR1 (0.51) | SIGMAR1HRH3CPA1CPB1CPA3 | |
| SCHEMBL8449054 | 0.99 | HRH3 (0.52) | SIGMAR1HRH3CPA1CPB1CPA3 | |
| SCHEMBL7288419 | 0.90 | TACR2 (0.50) | SIGMAR1CPA1CPB1CPA3CPB2 | |
| SCHEMBL8799680 | 0.90 | TACR2 (0.50) | SIGMAR1CPA1CPB1CPA3CPB2 | |
| SCHEMBL7351373 | 0.87 | CPA1 (0.47) | HRH3CPA1CPB1CPA3CPB2 | |
| SCHEMBL7280064 | 0.80 | CPA1 (0.57) | CPA1CPB1CPA3CPB2CYP1A2 | |
| Hydrochloric Acid SCHEMBL10449746 | 0.79 | CPA1 (0.55) | CPA1CPB1CPA3CPB2CHRM1 | |
| SCHEMBL8800452 | 0.78 | ALDH1A1 (0.47) | SIGMAR1 | |
| SCHEMBL7298846 | 0.78 | REN (0.46) | CPA1CPB1CPA3CPB2CYP1A2 | |
| SCHEMBL7274920 | 0.77 | CPA1 (0.60) | CPA1CPB1CPA3CPB2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410260-A2 | Peptidyl aminodiol renin inhibitors | ABBOTT LABORATORIES (US) | 1991-01-30 | — | — | EP | disclosed |