Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.56 |
| ▸ | ICMT | O60725 | 6/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.43 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.43 |
| ▸ | HTR1D | P28221 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334745 | 0.81 | HTR1D (0.64) | HTR1DHTR2AHTR1BHTR1AHTR2C | |
| SCHEMBL6574193 | 0.80 | CSNK2A1 (0.61) | CSNK2A1ICMTMPOSLC6A4 | |
| SCHEMBL14970013 | 0.78 | CSNK2A1 (0.67) | CSNK2A1ICMTHTR1DHTR2AHTR1B | |
| SCHEMBL7327470 | 0.77 | HTR1D (0.62) | HTR1DHTR2AHTR1BHTR1AHTR2C | |
| SCHEMBL7325786 | 0.77 | CSNK2A1 (0.55) | CSNK2A1ICMTMPOSLC6A4GPR84 | |
| SCHEMBL7335081 | 0.76 | CSNK2A1 (0.60) | CSNK2A1ICMTHTR2AMPOSLC6A4 | |
| SCHEMBL7327065 | 0.76 | CSNK2A1 (0.60) | CSNK2A1ICMTHTR2AHTR1AMPO | |
| SCHEMBL7333301 | 0.76 | CSNK2A1 (0.56) | CSNK2A1HTR1DHTR2AHTR1BHTR1A | |
| SCHEMBL274224 | 0.75 | CSNK2A1 (0.67) | CSNK2A1HTR1DHTR2AHTR1BHTR1A | |
| SCHEMBL7359803 | 0.75 | CSNK2A1 (0.55) | CSNK2A1ICMTMPOSLC6A4GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674620-A1 | TRYPTAMINE ANALOGUES AS 5-HT 1?-LIKE AGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014771-A1 | TRYPTAMINE ANALOGUES AS 5-HT1-LIKE AGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-07-07 | — | — | WO | disclosed |