Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.60 |
| ▸ | MPO | P05164 | 10/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.55 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | ICMT | O60725 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2724522 | 0.88 | MPO (0.68) | CSNK2A1MPOSLC6A4GPR84HTR2A | |
| SCHEMBL6574193 | 0.87 | CSNK2A1 (0.61) | CSNK2A1MPOSLC6A4ICMTDRD2 | |
| SCHEMBL7335081 | 0.85 | CSNK2A1 (0.60) | CSNK2A1MPOSLC6A4GPR84HTR2A | |
| SCHEMBL4945471 | 0.85 | CSNK2A1 (0.56) | CSNK2A1MPOSLC6A4GPR84ICMT | |
| SCHEMBL7333301 | 0.82 | CSNK2A1 (0.56) | CSNK2A1SLC6A4GPR84HTR2ATRPM8 | |
| SCHEMBL29352833 | 0.78 | GPR84 (0.67) | CSNK2A1MPOSLC6A4GPR84HTR2A | |
| SCHEMBL1242939 | 0.78 | GPR84 (0.67) | CSNK2A1MPOSLC6A4GPR84HTR2A | |
| SCHEMBL2537905 | 0.78 | MPO (0.77) | MPOSLC6A4HTR2ATRPM8HTR1A | |
| SCHEMBL7326928 | 0.76 | CSNK2A1 (0.56) | CSNK2A1MPOSLC6A4GPR84HTR2A | |
| SCHEMBL2004780 | 0.75 | CSNK2A1 (0.67) | CSNK2A1SLC6A4HTR2AHTR1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674620-A1 | TRYPTAMINE ANALOGUES AS 5-HT 1?-LIKE AGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014771-A1 | TRYPTAMINE ANALOGUES AS 5-HT1-LIKE AGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-07-07 | — | — | WO | disclosed |