Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.55 |
| ▸ | PIM1 | P11309 | 3/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ICMT | O60725 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6574193 | 0.82 | CSNK2A1 (0.61) | CSNK2A1MPOSLC6A4ICMT | |
| SCHEMBL7326496 | 0.80 | HTR1D (0.57) | MPOMAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7331855 | 0.77 | HTR1D (0.60) | MPOSLC6A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7325786 | 0.76 | CSNK2A1 (0.55) | CSNK2A1GPR84MPOSLC6A4MAPT | |
| SCHEMBL8868448 | 0.75 | CSNK2A1 (0.53) | CSNK2A1GPR84MAPTCYP1A2CYP2D6 | |
| SCHEMBL7335081 | 0.75 | CSNK2A1 (0.60) | CSNK2A1GPR84MPOSLC6A4MAPT | |
| SCHEMBL7327065 | 0.75 | CSNK2A1 (0.60) | CSNK2A1GPR84MPOSLC6A4ICMT | |
| SCHEMBL7326928 | 0.75 | CSNK2A1 (0.56) | CSNK2A1GPR84MPOSLC6A4ICMT | |
| SCHEMBL10582041 | 0.74 | GRM4 (0.51) | CSNK2A1 | |
| SCHEMBL31370163 | 0.73 | KMT2A (0.62) | MPOSLC6A4MAPTICMTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674620-A1 | TRYPTAMINE ANALOGUES AS 5-HT 1?-LIKE AGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014771-A1 | TRYPTAMINE ANALOGUES AS 5-HT1-LIKE AGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-07-07 | — | — | WO | disclosed |