Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | ICMT | O60725 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | MC5R | P33032 | 1/20 | 0.41 |
| ▸ | MC1R | Q01726 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6574193 | 0.82 | CSNK2A1 (0.61) | CSNK2A1ICMTLTA4HPLA2G2AMPO | |
| SCHEMBL7325860 | 0.82 | LTA4H (0.59) | LTA4HPLA2G2AHTR6MAPTMPO | |
| Hydrochloric Acid SCHEMBL7312565 | 0.81 | LTA4H (0.61) | LTA4HPLA2G2AHTR6MAPTMPO | |
| SCHEMBL18552205 | 0.79 | TDO2 (0.47) | MCL1 | |
| SCHEMBL7324142 | 0.79 | HTR1A (0.60) | HTR6MPOSLC6A4 | |
| SCHEMBL7326928 | 0.77 | CSNK2A1 (0.56) | CSNK2A1ICMTGPR84MPOSLC6A4 | |
| SCHEMBL149254 | 0.76 | MEN1 (0.62) | CSNK2A1HTR6MAPTGPR84MPO | |
| SCHEMBL29521038 | 0.76 | MEN1 (0.62) | CSNK2A1HTR6MAPTGPR84MPO | |
| SCHEMBL7359803 | 0.76 | CSNK2A1 (0.55) | CSNK2A1ICMTMAPTGPR84MPO | |
| SCHEMBL7311018 | 0.76 | MCL1 (0.43) | MCL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674620-A1 | TRYPTAMINE ANALOGUES AS 5-HT 1?-LIKE AGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-10-04 | — | — | EP | disclosed |
| CN-1092765-A | New tryptamine analogues and preparation method thereof and purposes | SMITHKLINE BEECHAM PLC (GB) | 1994-09-28 | — | — | CN | disclosed |
| WO-1994014771-A1 | TRYPTAMINE ANALOGUES AS 5-HT1-LIKE AGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-07-07 | — | — | WO | disclosed |