Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | IL6ST | P40189 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9220378 | 0.92 | KMT2A (0.45) | MAPTPOLBPKMSMN1; SMN2IL6ST | |
| SCHEMBL9220381 | 0.92 | KMT2A (0.45) | MAPTPOLBPKMSMN1; SMN2IL6ST | |
| SCHEMBL9220375 | 0.92 | KMT2A (0.45) | MAPTPOLBPKMSMN1; SMN2IL6ST | |
| SCHEMBL7439721 | 0.91 | FKBP1A (0.47) | MAPTPOLBPKMSMN1; SMN2IL6ST | |
| SCHEMBL7327072 | 0.91 | FKBP1A (0.47) | MAPTPOLBPKMSMN1; SMN2IL6ST | |
| SCHEMBL7439715 | 0.91 | FKBP1A (0.47) | MAPTPOLBPKMSMN1; SMN2IL6ST | |
| SCHEMBL9217062 | 0.78 | TDP1 (0.49) | MAPTSMN1; SMN2IL6ST | |
| SCHEMBL9217060 | 0.78 | TDP1 (0.49) | MAPTSMN1; SMN2IL6ST | |
| SCHEMBL9217065 | 0.78 | TDP1 (0.49) | MAPTSMN1; SMN2IL6ST | |
| SCHEMBL9219299 | 0.77 | MAPT (0.64) | MAPTPOLBPKMMMP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378689-A | Hypotensive agents; administrable by mouth | SANKYO COMPANY, LIMITED (JP) | 1995-01-03 | — | — | US | disclosed |