Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | IL6ST | P40189 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9220378 | 1.00 | KMT2A (0.45) | KMT2AMEN1POLBPKMIL6ST | |
| SCHEMBL9220381 | 1.00 | KMT2A (0.45) | KMT2AMEN1POLBPKMIL6ST | |
| SCHEMBL9214752 | 0.92 | MAPT (0.47) | KMT2AMEN1POLBPKMIL6ST | |
| SCHEMBL7439715 | 0.92 | FKBP1A (0.47) | KMT2AMEN1POLBPKMIL6ST | |
| SCHEMBL7327072 | 0.92 | FKBP1A (0.47) | KMT2AMEN1POLBPKMIL6ST | |
| SCHEMBL7439721 | 0.92 | FKBP1A (0.47) | KMT2AMEN1POLBPKMIL6ST | |
| SCHEMBL9217065 | 0.79 | TDP1 (0.49) | IL6STSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9217062 | 0.79 | TDP1 (0.49) | IL6STSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9217060 | 0.79 | TDP1 (0.49) | IL6STSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7268138 | 0.76 | KMT2A (0.56) | KMT2AMEN1POLBPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378689-A | Hypotensive agents; administrable by mouth | SANKYO COMPANY, LIMITED (JP) | 1995-01-03 | — | — | US | disclosed |