Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRACR2A | Q9BSW2 | 3/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.53 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.53 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.53 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | F9 | P00740 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326145 | 0.87 | CRACR2A (0.51) | CRACR2AEPHX2TRPC3ORAI1TRPC5 | |
| SCHEMBL7318316 | 0.87 | CRACR2A (0.51) | CRACR2AEPHX2TRPC3ORAI1TRPC5 | |
| SCHEMBL7319689 | 0.84 | EPHX2 (0.49) | CRACR2AEPHX2TRPC3ORAI1TRPC5 | |
| SCHEMBL7325134 | 0.78 | EPHX2 (0.57) | CRACR2AEPHX2TRPC3ORAI1KDM4E | |
| SCHEMBL8261714 | 0.77 | LMNA (0.54) | CRACR2ATRPC3ORAI1TRPC5LMNA | |
| SCHEMBL12615169 | 0.76 | RAB9A (0.68) | LMNAMAPTNPC1RAB9AMEN1 | |
| SCHEMBL7314753 | 0.73 | LMNA (0.60) | CRACR2ATRPC3ORAI1TRPC5LMNA | |
| SCHEMBL7318957 | 0.73 | CRACR2A (0.54) | CRACR2ATRPC3ORAI1TRPC5LMNA | |
| SCHEMBL7972108 | 0.73 | LMNA (0.84) | CRACR2ATRPC3ORAI1TRPC5LMNA | |
| SCHEMBL7323605 | 0.72 | TRPC3 (0.61) | CRACR2ATRPC3ORAI1TRPC5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010044445-A1 | AZOLE INHIBITORS OF CYTOKINE PRODUCTION | ABBOTT LABORATORIES | 2001-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010044445-A1 | AZOLE INHIBITORS OF CYTOKINE PRODUCTION | IL5, IL2, IL4 | CRACR2A 3286/4885EPHX2 732/4885TRPC3 4362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.