Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | CD44 | P16070 | 1/20 | 0.34 |
| ▸ | RGS12 | O14924 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29860884 | 0.88 | GID4 (0.46) | ADRA2AGID4ACHESLC6A2SLC6A3 | |
| SCHEMBL4014137 | 0.88 | GID4 (0.46) | ADRA2AGID4ACHESLC6A2SLC6A3 | |
| SCHEMBL1150666 | 0.81 | ADRA2A (0.43) | ADRA2ACYP11B1CYP11B2ACHESLC6A2 | |
| SCHEMBL3585626 | 0.81 | ADRA2A (0.43) | ADRA2ACYP11B1CYP11B2ACHESLC6A2 | |
| SCHEMBL1151017 | 0.79 | HTR2C (0.42) | CYP11B1CYP11B2ACHESLC6A2SLC6A3 | |
| SCHEMBL7012015 | 0.79 | ADRA2A (0.50) | ADRA2AGID4HSD17B2SLC6A2SLC6A3 | |
| SCHEMBL12674518 | 0.79 | ADRA2A (0.50) | ADRA2ACYP1A2CYP3A4CYP2D6DRD2 | |
| SCHEMBL17193124 | 0.79 | GID4 (0.42) | ADRA2AGID4CYP11B1CYP11B2ACHE | |
| SCHEMBL4743515 | 0.79 | ADRA2A (0.50) | ADRA2ACYP1A2CYP3A4CYP2D6DRD2 | |
| SCHEMBL29983834 | 0.79 | GID4 (0.42) | ADRA2AGID4CYP11B1CYP11B2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6051677-A | Gas separating membrane having a polycarbodiimide resin layer | NITTO DENKO CORPORATION (JP) | 2000-04-18 | — | — | US | disclosed |
| EP-0402923-A2 | 2,5-Diaminotetralines, process for their preparation and their use as medicine | BOEHRINGER INGELHEIM KG (DE) | 1990-12-19 | — | — | EP | disclosed |