SCHEMBL4014137

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29860884	1.00	GID4 (0.46)	GID4ACHEADRA2ADRD2DRD1
	SCHEMBL7327615	0.88	ADRA2A (0.51)	GID4ACHEADRA2ADRD2DRD1
	SCHEMBL24619626	0.81	ACHE (0.46)	ACHEDRD2DRD3IL1RNERAP2
	SCHEMBL165119	0.79	ACHE (0.45)	ACHEDRD2DRD3IL1RNERAP2
	SCHEMBL10939693	0.78	GID4 (0.45)	GID4ACHEADRA2ADRD2DRD1
	SCHEMBL1151092	0.78	ACHE (0.48)	ACHEADRA2ADRD2SLC6A2SLC6A4
	SCHEMBL193435	0.78	HTR2C (0.45)	ACHESLC6A2SLC6A4SLC6A3CYP2D6
	SCHEMBL4666253	0.78	DRD2 (0.53)	ACHEDRD2DRD3
	SCHEMBL4202381	0.78	DRD2 (0.53)	ACHEDRD2CYP1A2CYP3A4CYP2D6
	SCHEMBL4641247	0.78	GID4 (0.45)	GID4ADRA2ADRD2DRD1DRD5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.