Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7327615 | 0.79 | ADRA2A (0.51) | ADRA2AGID4HSD17B2SLC6A2SLC6A4 | |
| SCHEMBL24539163 | 0.74 | ADRA2A (0.47) | ADRA2AGID4HSD17B2SLC6A2SLC6A4 | |
| SCHEMBL27635382 | 0.74 | ADRA2A (0.47) | ADRA2AGID4HSD17B2SLC6A2SLC6A4 | |
| SCHEMBL7258183 | 0.73 | SIRT1 (0.47) | ADRA2AGID4HSD17B2 | |
| SCHEMBL7258104 | 0.73 | ADRA2A (0.46) | ADRA2AGID4HSD17B2ADRA1ACA1 | |
| SCHEMBL2215346 | 0.71 | MAPT (0.41) | LMNAMAPK1KMT2A | |
| SCHEMBL4014137 | 0.71 | GID4 (0.46) | ADRA2AGID4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29860884 | 0.71 | GID4 (0.46) | ADRA2AGID4SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL7332666 | 0.71 | ADRA2A (0.41) | ADRA2ACYP1A2CYP2D6HTR2AADRA1A | |
| SCHEMBL30968795 | 0.70 | HTR6 (0.47) | ADRA2AGID4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345888-A1 | METHOD FOR THE PRODUCTION OF 1,5-NAPHTHALENEDIAMINE | Bayer Aktiengesellschaft (DE) | 2003-09-24 | — | — | EP | claimed |
| WO-2002051792-A1 | METHOD FOR THE PRODUCTION OF 1,5-NAPHTHALENEDIAMINE | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-04 | — | — | WO | claimed |
| EP-1345888-A1 | METHOD FOR THE PRODUCTION OF 1,5-NAPHTHALENEDIAMINE | Bayer Aktiengesellschaft (DE) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002051792-A1 | METHOD FOR THE PRODUCTION OF 1,5-NAPHTHALENEDIAMINE | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-04 | — | — | WO | disclosed |