Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 2/20 | 0.43 |
| ▸ | CCR2 | P41597 | 2/20 | 0.43 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HLA-DRB1 | P01911 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7418021 | 1.00 | PDE4B (0.48) | PDE4BCTSLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7328284 | 0.98 | CTSL (0.47) | PDE4BCTSLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7359484 | 0.97 | PDE4B (0.49) | PDE4BCTSLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL1198333 | 0.86 | PDE4B (0.49) | PDE4BCTSLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL22988062 | 0.86 | PDE4B (0.49) | PDE4BCTSLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL14040698 | 0.81 | CTSK (0.57) | PDE4BCTSLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL4081547 | 0.80 | NAAA (0.61) | CTSLALDH1A1NAAAASAH1 | |
| SCHEMBL4087794 | 0.80 | NAAA (0.61) | CTSLALDH1A1NAAAASAH1 | |
| SCHEMBL10719082 | 0.80 | NAAA (0.61) | CTSLALDH1A1NAAAASAH1 | |
| SCHEMBL27605899 | 0.79 | KMT2A (0.51) | PDE4BCTSLSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527761-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | Beecham Group p.l.c. (GB) | 1993-02-24 | — | — | EP | disclosed |
| WO-1992006966-A1 | N-(2-ALKYL-3-MERCAPTOGLUTARYL)-AMINO-DIAZA CYCLOALKANONE DERIVATIVES AND THEIR USE AS COLLAGENASE INHIBITORS | BEECHAM GROUP PLC (GB) | 1992-04-30 | — | — | WO | disclosed |
| WO-1991015506-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | BEECHAM GROUP PLC (GB) | 1991-10-17 | — | — | WO | disclosed |