Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324428 | 0.84 | LTA4H (0.44) | LTA4HEPHX2HDAC1HDAC3HDAC4 | |
| SCHEMBL10376907 | 0.78 | LTA4H (0.43) | LTA4H | |
| SCHEMBL7320169 | 0.78 | LTA4H (0.43) | LTA4HEPHX2FFAR1FFAR4MGLL | |
| Hydrochloric Acid SCHEMBL7324002 | 0.77 | LTA4H (0.42) | LTA4H | |
| SCHEMBL20834076 | 0.73 | FFAR1 (0.77) | LTA4HEPHX2FFAR1FFAR4MGLL | |
| SCHEMBL8889196 | 0.73 | FFAR1 (0.77) | LTA4HEPHX2FFAR1FFAR4MGLL | |
| SCHEMBL28441593 | 0.72 | FFAR1 (0.79) | LTA4HEPHX2FFAR1FFAR4MGLL | |
| SCHEMBL10685473 | 0.71 | FFAR1 (0.61) | LTA4HEPHX2FFAR1FFAR4MGLL | |
| SCHEMBL10756304 | 0.70 | FFAR1 (0.67) | LTA4HEPHX2FFAR1FFAR4MGLL | |
| SCHEMBL12040562 | 0.70 | LTA4H (0.77) | LTA4HEPHX2FFAR1FFAR4MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |