Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.40 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7327990 | 0.84 | LTA4H (0.47) | LTA4HHDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL10378291 | 0.81 | LTA4H (0.39) | LTA4HHDAC1PSMB1PSMB5PSMB2 | |
| SCHEMBL7330386 | 0.81 | PSMB1 (0.42) | LTA4HPSMB1PSMB5PSMB2SYK | |
| SCHEMBL10378284 | 0.80 | LTA4H (0.45) | LTA4HHDAC1PSMB1PSMB5PSMB2 | |
| SCHEMBL7275476 | 0.75 | BCHE (0.56) | LTA4HHDAC1EPHX2 | |
| SCHEMBL7323405 | 0.74 | SYK (0.46) | SYK | |
| SCHEMBL6431215 | 0.73 | PRKCA (0.60) | LTA4HHDAC1SYKBCL2 | |
| SCHEMBL7322415 | 0.72 | SPHK1 (0.33) | — | |
| SCHEMBL7333441 | 0.72 | SPHK1 (0.33) | — | |
| SCHEMBL7328746 | 0.72 | SYK (0.38) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |