Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 3/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | USP7 | Q93009 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 3/20 | 0.42 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15757448 | 0.77 | FLT3 (0.65) | PIK3CAMIFFLT3USP7KDR | |
| SCHEMBL73153 | 0.76 | CDK2 (0.58) | PIK3CAMIFFLT3KDRPKM | |
| SCHEMBL73445 | 0.75 | MIF (0.60) | PIK3CAMIFFLT3KDRPKM | |
| SCHEMBL29845215 | 0.73 | PRMT5 (0.51) | FLT3GABRG2GABRB3GABRA3KDR | |
| SCHEMBL19153276 | 0.73 | KDM4E (0.47) | PIK3CAMIFFLT3KDRNPC1 | |
| SCHEMBL28255761 | 0.72 | TDO2 (0.55) | ADORA2AADORA1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL12848505 | 0.72 | PIK3CA (0.65) | PIK3CAMIFFLT3USP7RIPK2 | |
| SCHEMBL14138786 | 0.72 | MIF (0.60) | PIK3CAMIFFLT3GABRG2GABRB3 | |
| SCHEMBL3785577 | 0.71 | ALDH1A1 (0.50) | ADORA2ANPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL29492486 | 0.71 | ALDH1A1 (0.50) | ADORA2ANPC1ALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8131527-B1 | FGFR pharmacophore compounds | ASTEX THERAPEUTICS LTD. (GB) | 2012-03-06 | — | — | US | disclosed |