Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | BACE1 | P56817 | 2/20 | 0.50 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29492486 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CYP3A4BACE1PIN1PTPN1 | |
| Hydrochloric Acid SCHEMBL654303 | 0.98 | ALDH1A1 (0.53) | ALDH1A1CYP3A4BACE1PIN1PTPN1 | |
| SCHEMBL28255761 | 0.87 | TDO2 (0.55) | ALDH1A1CYP3A4BACE1HSD17B10KDM4E | |
| SCHEMBL3789140 | 0.85 | TDP1 (0.56) | ALDH1A1CYP3A4HSD17B10KDM4EHPGD | |
| SCHEMBL3789462 | 0.85 | ALDH1A1 (0.50) | ALDH1A1CYP3A4BACE1PIN1PTPN1 | |
| SCHEMBL5014862 | 0.84 | ALDH1A1 (0.52) | ALDH1A1BACE1HSD17B10SMN1; SMN2KMT2A | |
| SCHEMBL3790187 | 0.84 | CYP3A4 (0.58) | ALDH1A1CYP3A4HPGDSMN1; SMN2KMT2A | |
| SCHEMBL11004268 | 0.83 | ALDH1A1 (0.61) | ALDH1A1CYP3A4BACE1KDM4EHPGD | |
| SCHEMBL30206743 | 0.83 | ALDH1A1 (0.61) | ALDH1A1CYP3A4BACE1KDM4EHPGD | |
| SCHEMBL30206740 | 0.83 | ALDH1A1 (0.61) | ALDH1A1CYP3A4BACE1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112774731-A | Para-methoxy substituted palladium catalyst and application thereof in Heck reaction | 邹育英 | 2021-05-11 | — | — | CN | claimed |
| CN-117510368-A | Imidamine complex, double-matched iminamine nickel complex, preparation method, nickel-based catalyst and application | 中国石油天然气股份有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-112898352-B | Asymmetric palladium complex, preparation method and application thereof in catalyzing olefin polymerization | 中山大学 | 2022-03-22 | — | — | CN | disclosed |
| CN-112898352-A | Asymmetric palladium complex, preparation method and application thereof in catalyzing olefin polymerization | 中山大学 | 2021-06-04 | — | — | CN | disclosed |
| CN-112774731-A | Para-methoxy substituted palladium catalyst and application thereof in Heck reaction | 邹育英 | 2021-05-11 | — | — | CN | disclosed |
| US-20210107871-A1 | BIARYL SULFONAMIDE DERIVATIVE HAVING FILOVIRUS CELL ENTRY INHIBITION ACTIVITY | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2021-04-15 | — | — | US | disclosed |
| EP-3611161-A1 | BIARYL SULFONAMIDE DERIVATIVE HAVING FILOVIRUS CELL ENTRY INHIBITION ACTIVITY | National University Corporation Hokkaido University (JP) | 2020-02-19 | — | — | EP | disclosed |
| CN-103819345-B | A kind of preparation method of 2-aminobiphenyl derivate | WUXI GREEN SEPARATION TECHNOLOGY INSTITUTE CO., LTD. (CN) | 2015-08-05 | — | — | CN | disclosed |
| CN-103819345-A | Method for preparing 2-amino biphenyl derivative | WUXI GREEN SEPARATION TECHNOLOGY INST CO LTD | 2014-05-28 | — | — | CN | disclosed |
| EP-1558591-B1 | MODULATION OF ANXIETY THROUGH BLOCKADE OF ANANDAMIDE HYDROLYSIS | UNIV CALIFORNIA (US) | 2014-05-07 | — | — | EP | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| US-20060152143-A1 | White-emitting compounds, process for the production thereof, and white-emitting devices | HIROSE ENGINEERING CO., LTD. (JP) | 2006-07-13 | — | — | US | disclosed |
| EP-1650208-A1 | WHITE-EMITTING COMPOUNDS, PROCESS FOR THE PRODUCTION THEREOF, AND WHITE-EMITTING DEVICES | HIROSE ENGINEERING CO., LTD. (JP) | 2006-04-26 | — | — | EP | disclosed |
| CN-1678321-A | Methods of treating or preventing autoimmune diseases with 2, 4-pyrimidinediamine compounds | RIGEL PHARMACEUTICALS INC (US) | 2005-10-05 | — | — | CN | disclosed |
| CN-1028521-C | Therapeutic agents | BOOTS CO PLC (GB) | 1995-05-24 | — | — | CN | disclosed |
| EP-0536151-B1 | ORTHOSUBSTITUTED BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | BOOTS CO PLC (GB) | 1994-09-14 | — | — | EP | disclosed |
| US-5302720-A | Biphenyl-substituted guanidine derivatives useful as hypoglycaemic agents | THE BOOTS COMPANY (GB) | 1994-04-12 | — | — | US | disclosed |
| CN-1072173-A | Therapeutical agent | BOOTS CO PLC (GB) | 1993-05-19 | — | — | CN | disclosed |
| EP-0536151-A1 | ORTHOSUBSTITUTED BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM. | BOOTS CO PLC (GB) | 1993-04-14 | — | — | EP | disclosed |
| WO-1992000273-A1 | ORTHOSUBSTITUTED BIPHENYL AMIDINE AND BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | THE BOOTS COMPANY PLC (GB) | 1992-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060152143-A1 | White-emitting compounds, process for the production thereof, and white-emitting devices | IWS1, WNT1, CYP1A1 | ALDH1A1 39/4885CYP3A4 42/4885BACE1 141/4885 |
| US-20210107871-A1 | BIARYL SULFONAMIDE DERIVATIVE HAVING FILOVIRUS CELL ENTRY INHIBITION ACTIVITY | FLNA, FLNB, BRI3BP | ALDH1A1 2624/4885CYP3A4 1343/4885BACE1 3967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.