SCHEMBL7328060

SCHEMBL7328060

Cc1ccc(S(=O)(=O)N2CCC[C@@H]2OC(=O)O)cc1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.53
HPGD P15428 1/20 0.53
MAPK1 P28482 2/20 0.51
TSHR P16473 2/20 0.51
L3MBTL1 Q9Y468 1/20 0.50
KDM4E B2RXH2 2/20 0.49
ALDH1A1 P00352 2/20 0.49
POLB P06746 2/20 0.49
FKBP1A P62942 2/20 0.49
MEN1 O00255 1/20 0.49
MAPT P10636 1/20 0.49
KMT2A Q03164 1/20 0.49
HSD17B10 Q99714 1/20 0.49
NPSR1 Q6W5P4 1/20 0.48
RAB9A P51151 1/20 0.47
USP2 O75604 1/20 0.47
PLAU P00749 1/20 0.47
HPN P05981 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7981443 0.83 MAPK1 (0.52) GAAHPGDMAPK1TSHRL3MBTL1
SCHEMBL27949305 0.83 FKBP1A (0.53) GAAMAPK1TSHRL3MBTL1KDM4E
SCHEMBL696505 0.80 ALDH1A1 (0.68) GAAHPGDMAPK1TSHRL3MBTL1
SCHEMBL2636629 0.80 ALDH1A1 (0.68) GAAHPGDMAPK1TSHRL3MBTL1
SCHEMBL9217074 0.80 GAA (0.54) GAAHPGDMAPK1TSHRL3MBTL1
SCHEMBL696506 0.80 ALDH1A1 (0.68) GAAHPGDMAPK1TSHRL3MBTL1
SCHEMBL7329088 0.80 AKR1C3 (0.56) HPGDTSHRKDM4EALDH1A1
Hydrochloric Acid SCHEMBL4077466 0.79 ALDH1A1 (0.67) GAAHPGDMAPK1TSHRL3MBTL1
SCHEMBL6842733 0.79 PSEN1 (0.50) GAAHPGDMAPK1TSHRL3MBTL1
Hydrochloric Acid SCHEMBL4077465 0.79 ALDH1A1 (0.67) GAAHPGDMAPK1TSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0420120-B1 Optically active benzyl alcohol compound and pharmaceutical composition HOKURIKU PHARMACEUTICAL (JP) 1994-08-31 EP claimed