Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6842733 | 0.95 | PSEN1 (0.50) | MAPK1TSHRGAAHPGDL3MBTL1 | |
| SCHEMBL28243001 | 0.87 | TRPA1 (0.61) | TSHRNPSR1ALDH1A1PKMMAPT | |
| SCHEMBL27976150 | 0.87 | HCRTR1 (0.50) | ALDH1A1HTTMAPTLMNA | |
| SCHEMBL27976149 | 0.87 | HCRTR1 (0.50) | ALDH1A1HTTMAPTLMNA | |
| SCHEMBL28242970 | 0.87 | TRPA1 (0.61) | TSHRNPSR1ALDH1A1PKMMAPT | |
| SCHEMBL27506312 | 0.83 | NPSR1 (0.48) | MAPK1TSHRGAAHPGDL3MBTL1 | |
| SCHEMBL7328060 | 0.83 | GAA (0.53) | MAPK1TSHRGAAHPGDL3MBTL1 | |
| SCHEMBL27758830 | 0.82 | GHSR (0.50) | TSHRALDH1A1HTTLMNA | |
| SCHEMBL15013036 | 0.81 | CASP3 (0.64) | RAB9APAX8 | |
| SCHEMBL12169307 | 0.81 | CASP3 (0.64) | RAB9APAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6225306-B1 | PYRROLO(1,2A)QUINOXALINES | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 2001-05-01 | — | — | US | disclosed |
| EP-0987266-A1 | BIPHENYL DERIVATIVES AND MEDICINAL COMPOSITIONS | Wakamoto Pharmaceutical Co., Ltd. (JP) | 2000-03-22 | — | — | EP | disclosed |