Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 15/20 | 0.51 |
| ▸ | CTSD | P07339 | 4/20 | 0.49 |
| ▸ | REN | P00797 | 3/20 | 0.47 |
| ▸ | CTSE | P14091 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328124 | 1.00 | BACE1 (0.51) | BACE1CTSDRENCTSE | |
| SCHEMBL7330209 | 1.00 | BACE1 (0.51) | BACE1CTSDRENCTSE | |
| SCHEMBL7325544 | 0.91 | BACE1 (0.51) | BACE1CTSDRENCTSE | |
| SCHEMBL7325549 | 0.88 | BACE1 (0.45) | BACE1CTSDRENCTSE | |
| SCHEMBL7327920 | 0.81 | CTSD (0.45) | BACE1CTSDREN | |
| SCHEMBL7320110 | 0.76 | CTSD (0.50) | BACE1CTSDRENCTSE | |
| SCHEMBL7330281 | 0.76 | BACE1 (0.47) | BACE1CTSD | |
| SCHEMBL7330286 | 0.76 | BACE1 (0.47) | BACE1CTSD | |
| SCHEMBL10378306 | 0.76 | ADORA3 (0.41) | BACE1REN | |
| SCHEMBL7332264 | 0.74 | MAGI3 (0.43) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |