Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 2/20 | 0.55 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360039 | 0.86 | PGR (0.58) | L3MBTL1PGRHSD17B1HSD17B2MEN1 | |
| SCHEMBL7333133 | 0.83 | L3MBTL1 (0.56) | L3MBTL1PGRMEN1KMT2AKDM4E | |
| SCHEMBL10186896 | 0.81 | PGR (0.70) | L3MBTL1PGRMAPTSMN1; SMN2NR1I2 | |
| SCHEMBL27336368 | 0.79 | HSD17B1 (0.51) | PGRHSD17B1HSD17B2MEN1KMT2A | |
| SCHEMBL7324146 | 0.79 | KMT2A (0.55) | L3MBTL1PGRMEN1KMT2AMAPT | |
| SCHEMBL10186886 | 0.79 | L3MBTL1 (0.83) | L3MBTL1PGRMEN1KMT2AKDM4E | |
| SCHEMBL6297317 | 0.77 | HSD17B1 (0.77) | HSD17B1HSD17B2NPC1RAB9AALDH1A1 | |
| SCHEMBL22792328 | 0.77 | L3MBTL1 (0.56) | L3MBTL1PGRKMT2AALDH1A1MAPT | |
| SCHEMBL7267305 | 0.75 | PGR (0.82) | L3MBTL1PGRMEN1KMT2AKDM4E | |
| SCHEMBL7337429 | 0.75 | KMT2A (0.54) | HSD17B1HSD17B2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |
| EP-0687253-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | Roche Diagnostics GmbH (DE) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020467-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1994-09-15 | — | — | WO | disclosed |