Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328316 | 0.86 | L3MBTL1 (0.56) | PGRL3MBTL1NPC1RAB9AKMT2A | |
| SCHEMBL7334990 | 0.84 | PGR (0.59) | PGRL3MBTL1KMT2AMEN1CA12 | |
| SCHEMBL7326459 | 0.80 | PGR (0.62) | PGRKMT2AMEN1LMNAHTT | |
| SCHEMBL7331867 | 0.80 | KMT2A (0.57) | PGRL3MBTL1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7332897 | 0.79 | KDM4E (0.52) | PGRL3MBTL1NPC1RAB9AHSD17B1 | |
| SCHEMBL7328298 | 0.79 | PGR (0.53) | PGRL3MBTL1KMT2AMEN1CA12 | |
| SCHEMBL7267305 | 0.79 | PGR (0.82) | PGRL3MBTL1KMT2AMEN1CA12 | |
| SCHEMBL10186886 | 0.75 | L3MBTL1 (0.83) | PGRL3MBTL1KMT2AMEN1CA12 | |
| SCHEMBL7811989 | 0.75 | CA12 (0.71) | L3MBTL1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL10186896 | 0.75 | PGR (0.70) | PGRL3MBTL1CA12CA9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | Roche Diagnostics GmbH (DE) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020467-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1994-09-15 | — | — | WO | disclosed |