Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP8 | P40818 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318548 | 0.84 | MAPT (0.40) | USP8RAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL7325771 | 0.75 | CRACR2A (0.50) | RAB9ASMN1; SMN2NPC1MAPTL3MBTL1 | |
| SCHEMBL7327369 | 0.75 | SMN1; SMN2 (0.40) | RAB9ASMN1; SMN2NPC1TSHRMAPT | |
| SCHEMBL7319005 | 0.71 | SMN1; SMN2 (0.35) | RAB9ASMN1; SMN2NPC1TSHRMAPT | |
| SCHEMBL7322949 | 0.70 | PTGS2 (0.51) | TSHRALDH1A1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL3374955 | 0.65 | CYP2A6 (0.52) | RAB9ASMN1; SMN2NPC1MAPTMEN1 | |
| SCHEMBL7324060 | 0.64 | USP8 (0.52) | USP8RAB9ASMN1; SMN2NPC1TSHR | |
| SCHEMBL21044243 | 0.61 | PRMT5 (0.49) | ALDH1A1TP53CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL23119810 | 0.60 | MKNK1 (0.52) | MAPTKMT2ACYP2A6 | |
| SCHEMBL612307 | 0.59 | CHRNB2 (0.40) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010044445-A1 | AZOLE INHIBITORS OF CYTOKINE PRODUCTION | ABBOTT LABORATORIES | 2001-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010044445-A1 | AZOLE INHIBITORS OF CYTOKINE PRODUCTION | IL5, IL2, IL4 | USP8 4088/4885RAB9A 4227/4885SMN1; SMN2 4665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.