Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325882 | 0.83 | MEN1 (0.40) | SMN1; SMN2RAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL7327369 | 0.79 | SMN1; SMN2 (0.40) | SMN1; SMN2TSHRRAB9ANPC1LMNA | |
| SCHEMBL7328425 | 0.71 | USP8 (0.38) | SMN1; SMN2TSHRRAB9ANPC1LMNA | |
| SCHEMBL7322949 | 0.70 | PTGS2 (0.51) | TSHRALDH1A1PTGS2PTGS1 | |
| SCHEMBL3188837 | 0.61 | PCSK9 (0.50) | TSHRRAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL8434538 | 0.57 | SCN9A (0.35) | — | |
| SCHEMBL31603854 | 0.57 | ALOX15 (0.41) | SMN1; SMN2TSHRRAB9ANPC1LMNA | |
| SCHEMBL2614367 | 0.57 | ALOX15 (0.59) | SMN1; SMN2RAB9ANPC1LMNAMAPT | |
| SCHEMBL7800845 | 0.56 | PRKCI (0.39) | SMN1; SMN2TSHRRAB9ANPC1LMNA | |
| SCHEMBL6871689 | 0.56 | PRKCI (0.39) | SMN1; SMN2TSHRRAB9ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010044445-A1 | AZOLE INHIBITORS OF CYTOKINE PRODUCTION | ABBOTT LABORATORIES | 2001-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010044445-A1 | AZOLE INHIBITORS OF CYTOKINE PRODUCTION | IL5, IL2, IL4 | SMN1; SMN2 4665/4885TSHR 4122/4885RAB9A 4227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.