SCHEMBL7328622

SCHEMBL7328622

COC(=O)[C@H](CC(C)C)NC(=O)OCC[Si](C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 13/20 0.46
TAS1R1 Q7RTX1 13/20 0.46
BIRC2 Q13490 1/20 0.43
POLB P06746 1/20 0.43
FOLH1 Q04609 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9064135 0.88 PPID (0.46) TAS1R3TAS1R1BIRC2
SCHEMBL7335289 0.87 ALDH1A1 (0.51) FOLH1
SCHEMBL7032142 0.85 MME (0.36) TAS1R3TAS1R1
SCHEMBL28537199 0.84 KDM4E (0.33) TAS1R3TAS1R1SMN1; SMN2
SCHEMBL16862569 0.84 KDM4E (0.33) TAS1R3TAS1R1SMN1; SMN2
SCHEMBL7327847 0.83 BIRC2 (0.46) TAS1R3TAS1R1BIRC2FOLH1
SCHEMBL23781491 0.83 CHRNB2 (0.35) FOLH1
SCHEMBL20338029 0.83 CASP1 (0.36)
SCHEMBL17841822 0.83 CASP1 (0.36)
SCHEMBL16862539 0.83 CHRNB2 (0.35) FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0393457-B1 Proteinase inhibitor SUNTORY LTD (JP) 1994-07-06 EP disclosed
EP-0393457-A1 Proteinase inhibitor SUNTORY LIMITED (JP) 1990-10-24 EP disclosed