Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32670415 | 0.88 | LMNA (0.47) | LMNAGAAKDM4EHSD17B10CASP1 | |
| SCHEMBL6988115 | 0.81 | LMNA (0.42) | LMNAGAAKDM4EHSD17B10CASP1 | |
| SCHEMBL8368989 | 0.80 | OPRM1 (0.62) | OPRM1GAA | |
| SCHEMBL7421566 | 0.80 | OPRM1 (0.65) | OPRM1LMNAKDM4EHSD17B10CASP1 | |
| SCHEMBL20978162 | 0.78 | ALDH1A1 (0.43) | OPRM1HSD17B10ALDH1A1HPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL25263821 | 0.77 | ALDH1A1 (0.42) | OPRM1HSD17B10ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL26638645 | 0.76 | OPRM1 (0.56) | OPRM1GAA | |
| SCHEMBL16915621 | 0.75 | SLC6A9 (0.47) | SLC6A9 | |
| SCHEMBL6803691 | 0.75 | LMNA (0.44) | OPRM1LMNAGAAKDM4EHSD17B10 | |
| SCHEMBL16926658 | 0.74 | SLC6A9 (0.42) | SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691959-A1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994022834-A1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |