Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7327875 | 0.91 | KMT2A (0.39) | STAT3CTDSP1SIRT5KMT2ASMN1; SMN2 | |
| SCHEMBL7335918 | 0.74 | STAT3 (0.40) | STAT3CTDSP1SIRT5KMT2ASMN1; SMN2 | |
| SCHEMBL7328403 | 0.69 | SMN1; SMN2 (0.40) | KMT2ASMN1; SMN2LMNAESR1ALDH1A1 | |
| SCHEMBL6896594 | 0.68 | ALDH1A1 (0.45) | KMT2ASMN1; SMN2ALDH1A1MEN1CYP2C9 | |
| SCHEMBL7325433 | 0.67 | PSMD10 (0.43) | STAT3CTDSP1SIRT5KMT2ASMN1; SMN2 | |
| SCHEMBL2965923 | 0.66 | KDM4E (0.43) | KMT2ASMN1; SMN2LMNAESR1ALDH1A1 | |
| SCHEMBL7333041 | 0.66 | KDM4E (0.51) | KMT2AALDH1A1MEN1POLBMAPT | |
| SCHEMBL7327836 | 0.65 | KMT2A (0.38) | STAT3CTDSP1SIRT5KMT2ASMN1; SMN2 | |
| SCHEMBL10739653 | 0.65 | KDM4E (0.42) | KMT2ASMN1; SMN2LMNAESR1ALDH1A1 | |
| SCHEMBL14778175 | 0.64 | ALDH1A1 (0.42) | KMT2ASMN1; SMN2ALDH1A1MEN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4924010-A | GASTROINTESTINAL DISORDERS | RORER PHARMACEUTICAL CORPORATION (US) | 1990-05-08 | — | — | US | disclosed |
| US-4859683-A | Certain benzoxepins and their pharmaceutical compositions and methods | RORER PHARMACEUTICAL CORPORATION (US) | 1989-08-22 | — | — | US | disclosed |
| US-4857517-A | Quinuclidyl benzoxepins as 5-HT3 antagonists | RORER PHARMACEUTICAL CORPORATION (US) | 1989-08-15 | — | — | US | disclosed |