Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 8/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.40 |
| ▸ | ACSL6 | Q9UKU0 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7320442 | 0.99 | LMNA (0.47) | LMNAMAPTNPC1MAOBHRH3 | |
| SCHEMBL7324169 | 0.88 | LMNA (0.46) | LMNAMAPTNPC1MAOBHRH3 | |
| Hydrochloric Acid SCHEMBL7321268 | 0.87 | LMNA (0.46) | LMNAMAPTNPC1MAOBHRH3 | |
| SCHEMBL7325472 | 0.86 | MAOB (0.49) | LMNAMAPTNPC1MAOBHRH3 | |
| Hydrochloric Acid SCHEMBL7331659 | 0.85 | MAOB (0.48) | LMNAMAOBHRH3BCHEACHE | |
| SCHEMBL905368 | 0.79 | LSS (0.44) | LMNAMAPTNPC1ACSL1ACSL6 | |
| SCHEMBL3221853 | 0.77 | CHRNB4 (0.46) | MAPTNPSR1CHRM2CHRM1CHRM3 | |
| SCHEMBL3221856 | 0.77 | CHRNB4 (0.46) | MAPTNPSR1CHRM2CHRM1CHRM3 | |
| SCHEMBL3221893 | 0.77 | CHRNB4 (0.46) | MAPTNPSR1CHRM2CHRM1CHRM3 | |
| SCHEMBL7328652 | 0.75 | LTA4H (0.46) | MAPTHRH3NPSR1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625979-A1 | AZABRICYCLIC COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-11-30 | — | — | EP | claimed |
| WO-1993015073-A1 | AZABRICYCLIC COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-08-05 | — | — | WO | claimed |