Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDCBP | O00560 | 1/20 | 0.35 |
| ▸ | SDC2 | P34741 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | NMT2 | O60551 | 1/20 | 0.32 |
| ▸ | NMT1 | P30419 | 1/20 | 0.32 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.32 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324372 | 1.00 | SDCBP (0.35) | SDCBPSDC2CASP1NMT2NMT1 | |
| SCHEMBL9754459 | 0.86 | CTSD (0.34) | CASP1NMT2NMT1ERAP2ERAP1 | |
| SCHEMBL7328882 | 0.86 | CNR2 (0.33) | NMT2NMT1OPRD1SPHK1OPRM1 | |
| SCHEMBL7322415 | 0.86 | SPHK1 (0.33) | NMT2NMT1OPRD1SPHK1OPRM1 | |
| SCHEMBL7333441 | 0.86 | SPHK1 (0.33) | NMT2NMT1OPRD1SPHK1OPRM1 | |
| SCHEMBL7332114 | 0.86 | CASP1 (0.41) | CASP1OPRD1SPHK1OPRM1OPRK1 | |
| SCHEMBL7320867 | 0.86 | CASP1 (0.41) | CASP1OPRD1SPHK1OPRM1OPRK1 | |
| SCHEMBL7330032 | 0.81 | ERAP2 (0.33) | ERAP2ERAP1SPHK1 | |
| SCHEMBL7330004 | 0.81 | ERAP2 (0.33) | ERAP2ERAP1SPHK1 | |
| SCHEMBL7324031 | 0.79 | CASP1 (0.38) | CASP1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |