Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.33 |
| ▸ | NMT2 | O60551 | 1/20 | 0.32 |
| ▸ | NMT1 | P30419 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 2/20 | 0.30 |
| ▸ | CNR2 | P34972 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322415 | 1.00 | SPHK1 (0.33) | SPHK1NMT2NMT1OPRD1OPRM1 | |
| SCHEMBL7328882 | 0.89 | CNR2 (0.33) | SPHK1NMT2NMT1OPRD1OPRM1 | |
| SCHEMBL7330004 | 0.86 | ERAP2 (0.33) | SPHK1 | |
| SCHEMBL7330032 | 0.86 | ERAP2 (0.33) | SPHK1 | |
| SCHEMBL7324372 | 0.86 | SDCBP (0.35) | SPHK1NMT2NMT1OPRD1OPRM1 | |
| SCHEMBL7328954 | 0.86 | SDCBP (0.35) | SPHK1NMT2NMT1OPRD1OPRM1 | |
| SCHEMBL7322952 | 0.80 | CTSS (0.32) | — | |
| SCHEMBL7329470 | 0.80 | CTSS (0.32) | — | |
| SCHEMBL9754459 | 0.77 | CTSD (0.34) | NMT2NMT1CNR1CNR2 | |
| SCHEMBL10378981 | 0.76 | LTA4H (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | claimed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | claimed |
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |