Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10910692 | 0.88 | CTSS (0.45) | CTSKCTSS | |
| SCHEMBL7337054 | 0.86 | CTSL (0.43) | CTSKCTSSCTSLCTSB | |
| SCHEMBL8927576 | 0.82 | CTSS (0.38) | CTSKCTSS | |
| SCHEMBL4662788 | 0.81 | CTSK (0.44) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4662787 | 0.81 | CTSK (0.44) | CTSKCTSSCTSLCTSB | |
| SCHEMBL7258777 | 0.80 | CTSS (0.45) | CTSKCTSS | |
| SCHEMBL4665934 | 0.80 | CTSK (0.43) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4665932 | 0.80 | CTSK (0.43) | CTSKCTSSCTSLCTSB | |
| SCHEMBL7398209 | 0.79 | CTSL (0.41) | CTSKCTSSCTSLCTSB | |
| SCHEMBL7325161 | 0.78 | CTSK (0.54) | CTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166154-A | Inhibitors of human neutrophil elastase | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1992-11-24 | — | — | US | disclosed |