Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329222 | 0.82 | CTSK (0.44) | CTSSCTSK | |
| SCHEMBL7337054 | 0.80 | CTSL (0.43) | CTSSCTSK | |
| SCHEMBL7398209 | 0.79 | CTSL (0.41) | CTSSCTSK | |
| SCHEMBL7564794 | 0.78 | CTSL (0.41) | CTSSCTSK | |
| SCHEMBL10910692 | 0.77 | CTSS (0.45) | CTSSCTSKKMT2A | |
| SCHEMBL3525420 | 0.74 | EPHX2 (0.39) | — | |
| SCHEMBL7572761 | 0.73 | CTSL (0.40) | CTSSCTSKKMT2A | |
| SCHEMBL7025316 | 0.73 | EPHX2 (0.36) | — | |
| SCHEMBL4665948 | 0.72 | CTSK (0.42) | CTSSCTSKKMT2ACACNA1B | |
| SCHEMBL5527345 | 0.72 | CTSK (0.42) | CTSSCTSKKMT2ACACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677448-A | CHEMICAL INTERMEDIATES FOR MAKING ANTAGONIST OF THROMBIN, TREATING THROMBOSIS, STROKE, INFLAMMATION, ARTERIOSCLEROSIS, CARDIOVASCULAR DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1997-10-14 | — | — | US | disclosed |
| US-5405854-A | Anticoagulants | HOFFMANN-LA ROCHE INC. (US) | 1995-04-11 | — | — | US | disclosed |