Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322870 | 0.85 | SLC1A3 (0.53) | ALDH1A1TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL14146579 | 0.84 | ALDH1A1 (0.56) | GBA1ALDH1A1TSHRCA12CYP1A2 | |
| SCHEMBL15257258 | 0.84 | GBA1 (0.60) | GBA1ALDH1A1TSHRCA12CYP1A2 | |
| Hydrochloric Acid SCHEMBL6739598 | 0.81 | GBA1 (0.65) | GBA1ALDH1A1TSHRSLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL6739604 | 0.81 | GBA1 (0.65) | GBA1ALDH1A1TSHRSLC1A3SLC1A2 | |
| Aspartic Acid SCHEMBL8667052 | 0.79 | MMP1 (0.51) | GBA1ALDH1A1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL6250115 | 0.79 | SLC1A3 (0.60) | GBA1ALDH1A1TSHRSLC1A3SLC1A2 | |
| SCHEMBL27850983 | 0.78 | CA9 (0.61) | GBA1ALDH1A1TSHRCA12CYP1A2 | |
| SCHEMBL8844329 | 0.78 | GBA1 (1.00) | GBA1ALDH1A1TSHRSLC1A3SLC1A2 | |
| SCHEMBL8844331 | 0.78 | GBA1 (1.00) | GBA1ALDH1A1TSHRSLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264457-A | Phenyl amidines sulfonamides useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1993-11-23 | — | — | US | disclosed |
| WO-1993016038-A1 | PHENYL AMIDINES SULFONAMIDES USEFUL AS PLATELET AGGREGATION INHIBITORS | G. D. SEARLE & CO. (US) | 1993-08-19 | — | — | WO | disclosed |