Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.53 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7798915 | 0.85 | ALDH1A1 (0.54) | ALDH1A1PKMTSHRCA2MMP2 | |
| SCHEMBL7329249 | 0.85 | GBA1 (0.63) | SLC1A3SLC1A2SLC1A1ALDH1A1TSHR | |
| SCHEMBL4173740 | 0.78 | MEP1B (0.67) | ALDH1A1PKMTSHRCA2MMP2 | |
| SCHEMBL27451020 | 0.78 | ALDH1A1 (0.55) | SLC1A3SLC1A2SLC1A1ALDH1A1PKM | |
| SCHEMBL6321537 | 0.77 | ALDH1A1 (0.63) | ALDH1A1PKMTSHRCA2MMP2 | |
| SCHEMBL8029643 | 0.76 | ALDH1A1 (0.65) | ALDH1A1PKMCA2MMP2GAA | |
| SCHEMBL2945763 | 0.76 | ALDH1A1 (0.69) | ALDH1A1PKMTSHRMEP1BGAA | |
| SCHEMBL7391079 | 0.75 | KEAP1 (0.62) | SLC1A3SLC1A2SLC1A1CA2MMP2 | |
| SCHEMBL7425855 | 0.75 | KEAP1 (0.62) | SLC1A3SLC1A2SLC1A1CA2MMP2 | |
| SCHEMBL7413723 | 0.75 | MEP1B (0.62) | ALDH1A1PKMCA2MMP2MEP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264457-A | Phenyl amidines sulfonamides useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1993-11-23 | — | — | US | disclosed |
| WO-1993016038-A1 | PHENYL AMIDINES SULFONAMIDES USEFUL AS PLATELET AGGREGATION INHIBITORS | G. D. SEARLE & CO. (US) | 1993-08-19 | — | — | WO | disclosed |