Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 4/20 | 0.52 |
| ▸ | FNTB | P49356 | 4/20 | 0.52 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | RARG | P13631 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.48 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.48 |
| ▸ | GNPAT | O15228 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9069637 | 0.92 | OPRK1 (0.52) | FNTAFNTBPGGT1BCYP1A2CYP3A4 | |
| SCHEMBL11560458 | 0.87 | CPB2 (0.41) | FNTAFNTBPGGT1BGNPAT | |
| SCHEMBL9621957 | 0.85 | FNTA (0.52) | FNTAFNTBPGGT1BGNPAT | |
| SCHEMBL9621954 | 0.85 | FNTA (0.52) | FNTAFNTBPGGT1BGNPAT | |
| SCHEMBL7319942 | 0.84 | MME (0.61) | FNTAFNTBPGGT1B | |
| SCHEMBL9068962 | 0.84 | MME (0.54) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1711701 | 0.83 | GNPAT (0.52) | FNTAFNTBPGGT1BGNPAT | |
| SCHEMBL1711691 | 0.83 | GNPAT (0.52) | FNTAFNTBPGGT1BGNPAT | |
| SCHEMBL29540393 | 0.83 | GNPAT (0.52) | FNTAFNTBPGGT1BGNPAT | |
| SCHEMBL5966602 | 0.83 | GNPAT (0.52) | FNTAFNTBPGGT1BGNPAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474795-A | ANALGESICS, MERCAPTO-ALKANOYL AMINO ACIDS | E. R. SQUIBB & SONS, INC. (US) | 1984-10-02 | — | — | US | disclosed |
| US-4474799-A | Enkephalinase inhibitors | E. R. SQUIBB & SONS, INC. (US) | 1984-10-02 | — | — | US | disclosed |
| US-4401677-A | Enkephalinase inhibitors | E. R. SQUIBB & SONS, INC. (US) | 1983-08-30 | — | — | US | disclosed |