Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.38 |
| ▸ | FNTA | P49354 | 12/20 | 0.37 |
| ▸ | FNTB | P49356 | 12/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 12/20 | 0.37 |
| ▸ | GNPAT | O15228 | 1/20 | 0.37 |
| ▸ | NPY4R | P50391 | 4/20 | 0.36 |
| ▸ | NPY1R | P25929 | 3/20 | 0.36 |
| ▸ | NPY2R | P49146 | 3/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329184 | 0.89 | MME (0.40) | CPB2FOLH1GNPATNPY4RNPY1R | |
| SCHEMBL9068939 | 0.88 | NPY4R (0.43) | FOLH1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL7329266 | 0.87 | FNTA (0.52) | FNTAFNTBPGGT1BGNPAT | |
| SCHEMBL10921836 | 0.84 | CPB2 (0.57) | CPB2FOLH1 | |
| SCHEMBL9068526 | 0.83 | NPY4R (0.40) | CPB2FOLH1NPY4RNPY1RNPY2R | |
| SCHEMBL9069166 | 0.82 | NPY4R (0.43) | FOLH1FNTAFNTBPGGT1BNPY4R | |
| SCHEMBL11207356 | 0.81 | NPY4R (0.46) | FNTAFNTBPGGT1BNPY4RNPY1R | |
| SCHEMBL10919416 | 0.81 | NPY4R (0.39) | FOLH1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL11352509 | 0.80 | NPY4R (0.47) | FNTAFNTBPGGT1BNPY4RNPY1R | |
| SCHEMBL1718474 | 0.80 | GNPAT (0.53) | FOLH1GNPATNPY4RNPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4176235-A | ANGIOTENSIN COVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1979-11-27 | — | — | US | disclosed |